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23-Chem-B4 Biochemical Engineering: Undated paper

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  1. Question 1 Maximum Oxygen-Transfer Flux in a Stirred-Tank Bioreactor
  2. Question 2 First-Principles Derivation of the Michaelis–Menten Equation
  3. Question 3 Effective Diffusivity in an Immobilized-Enzyme Bead from the Observed Thiele Modulus
  4. Question 4 Geometric Scale-Up of a Cell-Culture Bioreactor
  5. Question 5 High-Temperature Short-Time (HTST) Sterilization — Two Process Configurations

Start with Question 1 →

National Exam 16-Chem-B4, Biochemical Engineering — May 2019 (the header on page 1 reads "16-Chem-B4/May 2019"). 3 hours, Closed-Book Exam (approved Casio or Sharp calculator permitted). Per the exam notes, FIVE (5) questions constitute a complete paper and all five must be answered; each question is of equal value (20 marks) and short-essay-format answers are marked for clarity and organization.

Reference texts: Shuler & Kargi, Bioprocess Engineering: Basic Concepts, 2nd ed.; Bailey & Ollis, Biochemical Engineering Fundamentals, 2nd ed.; Fogler, Elements of Chemical Reaction Engineering, 4th ed. (Weisz–Prater / internal-diffusion criteria).

Interpretation notes: Two points where the printed question itself needs an interpretation are flagged where they are used: the meaning of p in the Question 1 solubility equation, and the definition of the observable Thiele modulus in Question 3.